Sitting all day, without taking breaks to stand up and walk around, puts you at risk for chronic diseases. Read this article in the Harvard Business Review that talks about how sitting is the smoking of our generation and great tips for how you can decrease your daily sitting time even on a busy schedule:

"After 1 hour of sitting, the production of enzymes that burn fat declines by as much as 90%. Extended sitting slows the body’s metabolism affecting things like (good cholesterol) HDL levels in our bodies. Research shows that this lack of physical activity is directly tied to 6% of the impact for heart diseases, 7% for type 2 diabetes, and 10% for breast cancer, or colon cancer....The New York Times reported on another study, published last year in the journal Circulation that looked at nearly 9,000 Australians and found that for each additional hour of television a person sat and watched per day, the risk of dying rose by 11%."